Kyle Sullivan Computational Systems Biologist Contact SULLIVANKA@ORNL.GOV All Publications Multiomic Network Analysis Identifies Dysregulated Neurobiological Pathways in Opioid Addiction An emerging multi-omic understanding of the genetics of opioid addiction A multi-ancestry genetic study of pain intensity in 598,339 veterans Analyses of GWAS signal using GRIN identify additional genes contributing to suicidal behavior RWRtoolkit: multi-omic network analysis using random walks on multiplex networks in any species... High dimensional predictions of suicide risk in 4.2 million US Veterans using ensemble transfer learning EpiPro, a Novel, Synthetic, Activity-Regulated Promoter That Targets Hyperactive Neurons in Epilepsy for Gene Therapy Applications Using iterative random forest to find geospatial environmental and Sociodemographic predictors of suicide attempts... Drug-Inducible Gene Therapy Effectively Reduces Spontaneous Seizures in Kindled Rats but Creates Off-Target Side Effects in Inhibitory Neurons The cholesterol transporter NPC1 is essential for epigenetic regulation and maturation of oligodendrocyte lineage cells Microglia are implicated in the development of paclitaxel chemotherapy-associated cognitive impairment in female mice Genetics of varicose veins reveals polygenic architecture and genetic overlap with arterial and venous disease Exploring the role of plant lysin motif receptor-like kinases in regulating plant-microbe interactions in the bioenergy crop Populus Antiviral Strategies Against SARS-CoV-2: A Systems Biology Approach A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci Key Links Curriculum Vitae Organizations Biological and Environmental Systems Science Directorate Biosciences Division Biocomputing and Information Section Computational and Predictive Biology Group
