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Imagine an instrument that collects thousands of diffraction data points in days instead of months with the help of a cylindrical image plate detector and an intense polychromatic neutron beam. IMAGINE is the newest single crystal diffractometer being installed at the High Flux Isotope Reactor, and ...
Researchers have long thought that formation of insoluble fibrous “strings” of self-assembling proteins might be involved in the progression of a number of diseases, including neurodegenerative disorders such as Alzheimer’s and Parkinson’s. However, recent evidence suggests that aggregates that develop at an earlier stage than fibril formation, and accumulate in human organs, may be the primary toxic agents.